Nashville, TN, October 5, 2025
News Summary
The Tennessee Titans, looking for their first win of the season, face off against the Arizona Cardinals in a critical Week 5 matchup. With a dismal 0-4 record, the Titans aim to shake off their recent shutout loss to the Houston Texans. Rookie quarterback Cam Ward and the struggling offense hope to improve against a mid-tier Cardinals squad. Injury concerns for both teams could play a significant role in this tight contest, making it crucial for the Titans to turn their season around.
Tennessee Titans Seek First Victory Against Arizona Cardinals in Week 5 Showdown
Nashville, TN – The Tennessee Titans are set to face the Arizona Cardinals in a crucial Week 5 matchup at State Farm Stadium. The Titans, currently struggling with an 0-4 record, are looking for their first victory of the season. The game will kick off on Sunday, October 5, 2025, at 4:05 EST and will be broadcast regionally on CBS.
In their last outing, the Titans faced a discouraging defeat, losing to the Houston Texans 26-0. This marked the Titans’ first shutout loss since 2019, leaving rookie quarterback Cam Ward feeling frustrated about his performance throughout the season. After four games, Ward has registered 614 passing yards, a 2-2 touchdown-interception ratio, and a completion rate of 51.2%.
The Titans have struggled on both ends of the field this season. Currently, they are the only team in the league without a win. In addition to Ward’s challenges, the team’s rushing attack is led by Tony Pollard, who has accumulated 261 rushing yards and one rushing touchdown. The Titans’ top receiver, Elic Ayomanor, has recorded 151 receiving yards along with two touchdowns.
Defensively, the Titans’ performance has been middle-of-the-road, with four sacks and three interceptions through four games. However, the team has struggled significantly with their offensive line, having allowed 17 sacks this season. Injury woes have also plagued the Titans, with T JC Latham, S Mike Brown, WR Bryce Oliver, and G Blake Hance ruled out, while WR Calvin Ridley is listed as questionable.
On the other side, the Arizona Cardinals come into this game with a 2-2 record. They last played on September 25, 2025, where they narrowly lost to the Seattle Seahawks 23-20. The Cardinals’ quarterback, Kyler Murray, has thrown for 742 passing yards with a 6-3 touchdown-interception ratio. However, the team has struggled to establish a running game, relying on Emari Demercado as the lead back due to injuries to James Connor and Trey Benson.
Among the Cardinals’ receiving corps, Marvin Harrison Jr. stands out with 208 receiving yards and two touchdowns. The Cardinals’ defense has been more effective, recording 8 sacks, with Calais Campbell contributing three sacks. Injury updates for the Cardinals indicate that RB Trey Benson, RB James Connor, and DT Bilal Nichols are out, while CB Denzel Burke, CB Will Johnson, and WR Greg Dortch are questionable for the game.
Predictions for the matchup suggest a low-scoring game, considering both teams’ offensive struggles. The Titans have covered the spread in only four of their last 20 games, and the betting odds indicate a total points under of 41.5.
Key Matchup Overview
| Team | Record | Last Game Result | Leading Stats | Injuries |
|---|---|---|---|---|
| Tennessee Titans | 0-4 | Lost to Houston Texans 26-0 | Cam Ward: 614 passing yards, Tony Pollard: 261 rushing yards | Out: T JC Latham, S Mike Brown, WR Bryce Oliver, G Blake Hance Questionable: WR Calvin Ridley |
| Arizona Cardinals | 2-2 | Lost to Seattle Seahawks 23-20 | Kyler Murray: 742 passing yards, Marvin Harrison Jr.: 208 receiving yards | Out: RB Trey Benson, RB James Connor, DT Bilal Nichols Questionable: CB Denzel Burke, CB Will Johnson, WR Greg Dortch |
Conclusion
As the Tennessee Titans head into Week 5 with the urgent need for a win, the showdown against the Arizona Cardinals poses significant challenges. Both teams are seeking to turn their seasons around, and the outcome of this game could set the tone for the weeks ahead.
FAQ Section
What time is the Titans vs. Cardinals game?
The game is scheduled for kickoff on Sunday, October 5, 2025, at 4:05 EST.
What is the current record of the Tennessee Titans?
The Titans have an 0-4 record going into this game.
Who leads the Titans in rushing yards?
Tony Pollard leads the Titans’ rushing attack with 261 yards and one rushing touchdown.
What is the injury status of the Titans?
Injury updates for the Titans include: Out – T JC Latham, S Mike Brown, WR Bryce Oliver, G Blake Hance; Questionable – WR Calvin Ridley.
What is the Arizona Cardinals’ current record?
The Arizona Cardinals start their game against the Titans with a 2-2 record.
Who is leading the Cardinals in passing yards?
Kyler Murray is the starting quarterback for the Cardinals with 742 passing yards and a 6-3 touchdown-interception ratio.
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Additional Resources
- Covers: Titans vs. Cardinals Predictions
- Wikipedia: Tennessee Titans
- Winners and Whiners: Titans vs. Cardinals Picks
- Google Search: Tennessee Titans vs Arizona Cardinals
- Tennessee Titans Official Site
- Encyclopedia Britannica: National Football League
- Titans Wire: Titans Activate Tyjae Spears
- Google News: Arizona Cardinals

Author: HERE Nashville
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